SOMNIA by Integer
Melatonin helps regulate the body’s circadian rhythm by promoting optimal sense of sleep cycles. Melatonin synthesis and secretion is enhanced by darkness and inhibited by light. The intensity of light information is transmitted from the retina to the pineal gland through the suprachiasmatic nucleus of the hypothalamus. In humans, its’ secretion starts soon after sundown, reaches a peak in the middle of the night and decreases gradually during the second half of the night. Due to extended screen times, demands on oxidative stress, shift work or alcohol consumption, melatonin can become deficient leading to chronic fatigue and tiredness. Somnia provides a micro-dose of melatonin per capsule, which helps support the natural production of melatonin and not inhibit the variable release throughout the night that can occur at higher doses.
Why these specific ingredients?
Pyridoxal 5’-Phosphate (P5P) – is the active form of Vitamin B6 that drives approximately 168 vital enzyme processes in our body. Among these vital roles P5P facilitates a process known as deamination — which is responsible for converting essential amino acids into non-essential ones. P5P also helps shuttle certain nutrients — such as magnesium — across cellular membranes which helps increase absorption rates. Pyridoxal 5’-Phosphate is a compound vital to our health, yet often found in short supply especially under stress. Vitamin B6 has been observed as being particularly synergistic in combination with magnesium. It is thought that pyridoxal 5`-phosphate is responsible for facilitating intercellular transportation of magnesium. Pyridoxial 5`-phosphate levels are inversely correlated to inflammatory markers such as Tumor Necrosis Factor Alpha (TNF-α) Interleukin 6 (IL-6) and Interferon Gamma (INF-γ). These markers are commonly used to accurately gauge the level of inflammation in response to certain medical conditions.
Magnesium Glycinate – is an important nutrient for the human body, because magnesium is part of many (300+) important processes that help maintain health, especially in the brain, heart, and muscles. One of the forms often used for magnesium deficiency is magnesium glycinate, which is magnesium bound to glycine. This type of magnesium has very good bioavailability. That means the body can make the most of it once it’s ingested. Magnesium glycinate has been shown to have a variety of benefits, including a calming effect on the brain due to the presence of glycine. It can help relieve anxiety and promote better sleep by relaxing the nervous system.
4-Amino-3-phenylbutanoic acid – is a GABA receptor agonist and increases dopamine response at low doses. Supports stress reduction and overall wellbeing. Helps support deep wave sleep.
L-Taurine – is a conditionally essential amino acid that can be formed in the body, but stores become low under certain conditions as well as bouts of stress. It is crucial in maintaining proper hydration and electrolyte balance in cells. Taurine plays a key role in controlling and calming your central nervous system by binding to the brain’s GABA receptors.
Phosphatidylserine – (PS) is an aminophospholipid and amino acid derivative which is produced naturally within the body however due to the typical diet, can be low in stores within the body especially under stress. PS also acts as a signaling agent for apoptosis, which is a standard process of cell death that is necessary for an organism to grow and develop. PS may play a role in reducing cortisol in your body, thus having a positive benefit on your stress levels. That goes for physical stress, like the kind you would experience from exercise, but PS also has an impact on reducing mental stress in social situations. PS can increase quantities of acetylcholine which may help to enhance memory. PS is synergistic with certain supplements and acts as a magnifier by improving the bioavailability of its paired supplements. PS especially works well with other lipophilic nutrients such as turmeric and phytocannabinoids such as CBD by enhancing their effects.
Hydrazorb™ CBD – (HZH) is Water Soluble THC-free Full Spectrum Hemp Powder containing a broad spectrum of cannabinoids including CBD. CBD balances the endocannabinoid system that is integrated into the body’s systems by modulating receptors. By improving these receptors, stress reduction occurs, sleep cycles improve, reduced inflammation and pain tolerance improvements are all observed. HZH Water Soluble Full Spectrum Hemp Powder contains CBD derived from American-grown USDA certified organic industrial hemp. HZH utilizes a specific quantifiable advanced technology platform that allows this product to dissolve into water at 100 times more potency than traditional CBD oil or CBD isolate powder. Hyrazorb™ Hemp is a water-soluble technology employing nano-cellular sized molecules under 100 NM in size. This technology creates increased cellular uptake into the body within a time frame of 7 seconds. The technology application that is infused into the Hydrazorb™ Hemp increases kinetic energy and bioavailability of the full spectrum hemp cannabinoids into the human system.
Suggested Use: Take only as needed for improved sleep cycles. Consume 30-60 minutes prior to bedtime. To assess tolerance, consume 2-3 capsules but do not exceed 4 capsules per day. After sleep cycles improve, reduce dosage and continue to use as needed from this time frame on.